Available Options
| Pack Size | Stock | Price | Quantity | |
|---|---|---|---|---|
| 10g | $51.70 | | ||
| 25g | $107.75 | | ||
| 50g | $172.50 | | ||
| 100g | $259.00 | | ||
| 500g | $990.00 | |
- About
- Additional information
- Case Studies
A clean, efficient catalyst that can be used from lab to plant scale across a range of transformations in the fine chemical, pharmaceutical, and bulk chemical industries.
The sulfonic acid functionality is covalently bound to the silica.
Esterification – 1,1,1-Tris(hydroxymethyl)propane + Octanoic acid + Phos-Cat4 combined and heated at 120 degrees C with overhead stirring under a gentle nitrogen flow for 16 hours. Reaction mixture decanted to separate the catalyst. Analysis showed the product to be >99.9% trimethylolpropane trisoctanote, recovered as a pale yellow oil. The catalyst was reused for over 20 cycles without loss of activity.
Elimination – 1-phenyl-1-cyclohexanol + toluene + Phos-Cat4 combined and stirred at reflux (110 degrees C) with water removal using Dean-Stark apparatus for 4 hours. Reaction mixture decanted and solvent removed by vacuum. Yield was 99.3% and purity by GC was 99.8%. Subsequent hydrogenation step proceeds smoothly, whereas use of pTSA results in poisoning of the Pd catalyst.
