WhoshouldIsee Tracks Phos-Cat1 – PhosphonicS




Ethyl/butyl phosphonic acid silica

SKU: CP156871 Category:

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A clean, efficient catalyst that can be used from lab to plant scale across a range of transformations in the fine chemical, pharmaceutical, and bulk chemical industries.

The phosphonic acid functionality is covalently bound to the silica.

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Pack Size

10g, 25g, 50g, 100g, 500g

Alcohol Protection – Tetrahydropyranylation: A mixture of alcohol, dihydropyran and Phos-Cat1 was stirred in ether. Following work-up, the tetrahydropyran derivative was isolated cleanly and in >98% yield.

Carbonyl Protection – Ketalisation: A mixture of ketone, ethylene glycol and Phos-Cat1 in toluene was refluxed under Dean and Stark. Following work-up the 1,3-dioxolane product was obtained in high purity and in >98% yield.

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